2IVS

Crystal structure of non-phosphorylated RET tyrosine kinase domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET	polymer	314	35708.2	2	UniProt (P07949) Pfam (PF07714)	HOMO SAPIENS (HUMAN)	RET RECEPTOR, C-RET
2	C, D, E, G, H... (A, B)	FORMIC ACID	non-polymer		46.0	6	Chemie (FMT)
3	F, J (A, B)	2',3'- cyclic AMP	non-polymer		329.2	2	Chemie (ACK)
4	K, L (A, B)	water	water		18.0	262	Chemie (HOH)

Sequence modifications

A, B: 700 - 704 (PDB: 2IVS)
A, B: 705 - 1013 (UniProt: P07949)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71416.5
Non-Polymers*	Number of molecules	8
	Total formula weight	934.6
All*	Total formula weight	72351.0

*Water molecules are not included.