2IUX
Human tACE mutant g1234
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | ANGIOTENSIN-CONVERTING ENZYME | polymer | 591 | 68325.2 | 1 | UniProt (P22966) Pfam (PF01401) UniProt (by SIFTS) (P12821) | HOMO SAPIENS (HUMAN) | HUMAN TACE G1234 MUTANT, TESTIS-SPECIFIC ISOFORM, ACE-T, DIPEPTIDYL CARBOXYPEPTIDASE I, KININASE II |
2 | B, C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
3 | D (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
4 | E (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
5 | F, G (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
6 | H (A) | N-CARBOXYALANINE | non-polymer | 133.1 | 1 | Chemie (NXA) | |||
7 | I (A) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A: 37 - 627 (UniProt: P22966)
PDB | External Database | Details |
---|---|---|
Gln 337 | Asn 368 | engineered mutation |
Gln 586 | Asn 617 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 68325.2 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 770.9 | |
All* | Total formula weight | 69096.1 |