2IUH
Crystal structure of the PI3-kinase p85 N-terminal SH2 domain in complex with c-Kit phosphotyrosyl peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT | polymer | 120 | 13939.6 | 1 | UniProt (P27986) Pfam (PF00017) | HOMO SAPIENS (HUMAN) | PI3-KINASE P85-ALPHA SUBUNIT, PTDINS-3-KINASE P85-ALPHA, PI3K |
| 2 | B (B) | C-KIT PHOSPHOTYROSYL PEPTIDE | polymer | 11 | 1365.4 | 1 | UniProt (Q8TCG9) UniProt (by SIFTS) (P10721) | HOMO SAPIENS (HUMAN) | |
| 3 | C, D (A, B) | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
A: 0 - 119 (UniProt: P27986)
| PDB | External Database | Details |
|---|---|---|
| Asn 9 | Asp 330 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 15305.0 | |
| All* | Total formula weight | 15305.0 |
