2IU3

Crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH	polymer	593	64497.7	2	UniProt (P31335) Pfam (PF02142) Pfam (PF01808)	GALLUS GALLUS (CHICKEN)	AMINOIMIDAZOLE CARBOXAMIDE RIBONUCLEOTIDE TRANSFORMYLASE AND IMP CYCLOHYDROLASE, ATIC, INOSINICASE, IMP AICAR TRANSFORMYLASE CYCLOHYDROLASE, IMP SYNTHETASE
2	C, D (A, B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
3	E (B)	1,5-DIHYDROIMIDAZO[4,5-C][1,2,6]THIADIAZIN-4(3H)-ONE 2,2-DIOXIDE	non-polymer		188.2	1	Chemie (203)
4	F, G (A, B)	water	water		18.0	97	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	128995.4
Non-Polymers*	Number of molecules	3
	Total formula weight	266.4
All*	Total formula weight	129261.8

*Water molecules are not included.