2IU0

crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase

Replaces:  2B0W

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH	polymer	593	64497.7	2	UniProt (P31335) Pfam (PF02142) Pfam (PF01808)	GALLUS GALLUS (CHICKEN)	PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE, 5-AMINOIMIDAZOLE-4-CARBOXAMIDE RIBONUCLEOTIDE FORMYLTRANSFERASE, AICAR TRANSFORMYLASE, IMP CYCLOHYDROLASE, ATIC, IMP SYNTHASE, INOSINICASE
2	C, D (A, B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
3	E (B)	1,5-DIHYDROIMIDAZO[4,5-C][1,2,6]THIADIAZIN-4(3H)-ONE 2,2-DIOXIDE	non-polymer		188.2	1	Chemie (203)
4	F, G (A, B)	water	water		18.0	253	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	128995.4
Non-Polymers*	Number of molecules	3
	Total formula weight	266.4
All*	Total formula weight	129261.8

*Water molecules are not included.