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2ITW

Crystal structure of EGFR kinase domain in complex with AFN941

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
EPIDERMAL GROWTH FACTOR RECEPTORpolymer32737304.11UniProt (P00533)
Pfam (PF07714)
HOMO SAPIENS (HUMAN)RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1
2B
(A)
1,2,3,4-Tetrahydrogen Staurosporinenon-polymer468.51Chemie (ITQ)
3C
(A)
waterwater18.072Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37304.1
Non-Polymers*Number of molecules1
Total formula weight468.5
All*Total formula weight37772.7
*Water molecules are not included.

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PDB entries from 2024-11-06

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