2ISO
Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-difluoromethylene triphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (T) | 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3' | polymer | 16 | 4829.1 | 1 | |||
| 2 | B (P) | 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3' | polymer | 10 | 3045.0 | 1 | |||
| 3 | C (D) | 5'-D(P*GP*TP*CP*GP*G)-3' | polymer | 5 | 1536.0 | 1 | |||
| 4 | D (A) | Polymerase (DNA directed), beta | polymer | 335 | 38241.7 | 1 | UniProt (Q3KP48) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) UniProt (by SIFTS) (P06746) | Homo sapiens (human) | |
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F, G, H (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 7 | I, J, K, L (A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 8 | M (A) | 2'-DEOXY-5'-O-[({[DIFLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL}OXY)(HYDROXY)PHOSPHORYL]GUANOSINE | non-polymer | 541.2 | 1 | Chemie (GFF) | |||
| 9 | N, O, P, Q (T, P, D, A) | water | water | 18.0 | 367 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 47651.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 776.3 | |
| All* | Total formula weight | 48428.1 |
