2ILZ
Crystal structure of poliovirus polymerase complexed with GTP and Mn2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | poliovirus polymerase | polymer | 461 | 52987.9 | 1 | UniProt (P03300) Pfam (PF00680) | Human poliovirus 1 | |
| 2 | B, C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) PubChem (27854) | |||
| 3 | D, E (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 4 | F (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 5 | G, H, I, J, K (A) | ACETIC ACID | non-polymer | 60.1 | 5 | Chemie (ACY) | |||
| 6 | L (A) | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
A: 1 - 461 (UniProt: P03300)
| PDB | External Database | Details |
|---|---|---|
| Cas 96 | Cys 1843 | modified residue |
| Cas 212 | Cys 1959 | modified residue |
| Cas 281 | Cys 2028 | modified residue |
| Cas 290 | Cys 2037 | modified residue |
| Asp 446 | Leu 2193 | engineered mutation |
| Asp 455 | Arg 2202 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52987.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 979.3 | |
| All* | Total formula weight | 53967.2 |
