2IJM
Crystal Structure of Focal Adhesion Kinase Domain with 2 molecules in the Asymmetric Unit Complexed with ADP and ATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Focal Adhesion Kinase 1 | polymer | 281 | 32231.2 | 2 | UniProt (Q05397) Pfam (PF07714) | Homo sapiens (human) | FADK 1; pp125FAK; Protein-tyrosine kinase 2 |
| 2 | C (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 3 | D (B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 184 | Chemie (HOH) |
Sequence modifications
A, B: 411 - 689 (UniProt: Q05397)
| PDB | External Database | Details |
|---|---|---|
| Gly 409 | - | cloning artifact |
| Ala 410 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64462.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 934.4 | |
| All* | Total formula weight | 65396.7 |
