2IJD
Crystal Structure of the Poliovirus Precursor Protein 3CD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (1, 2) | Picornain 3C, RNA-directed RNA polymerase | polymer | 644 | 72009.1 | 2 | UniProt (P03300) Pfam (PF00548) Pfam (PF00680) UniProt (by SIFTS) (Q1PHW8) | Human poliovirus 1 | Protease 3C, P3C, RNA-directed RNA polymerase, P3D, 3CD |
| 2 | C, H (1, 2) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, E, F, G, I... (1, 2) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 4 | M, N (1, 2) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
1, 2: 1 - 644 (UniProt: P03300)
| PDB | External Database | Details |
|---|---|---|
| Ala 55 | Glu 1619 | engineered mutation |
| Ala 58 | Asp 1622 | engineered mutation |
| Ala 63 | Glu 1627 | engineered mutation |
| Ala 147 | Cys 1711 | engineered mutation |
| Asp 629 | Leu 2193 | engineered mutation |
| Asp 638 | Arg 2202 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 144018.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 899.3 | |
| All* | Total formula weight | 144917.5 |
