2II5
Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Isobutyryl-Coenzyme A-bound form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex | polymer | 262 | 28726.6 | 8 | UniProt (P11181) Pfam (PF00198) | Bos taurus (cattle) | Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase, E2, Dihydrolipoamide branched chain transacylase, BCKAD E2 subunit |
| 2 | AA, BA, EA, FA, I... (E, F, A, G, B...) | ACETATE ION | non-polymer | 59.0 | 16 | Chemie (ACT) PubChem (175) | |||
| 3 | CA, GA, K, KA, L... (E, F, A, G, B...) | CHLORIDE ION | non-polymer | 35.5 | 12 | Chemie (CL) PubChem (312) | |||
| 4 | DA, HA, M, MA, Q... (E, F, A, G, B...) | ISOBUTYRYL-COENZYME A | non-polymer | 837.6 | 8 | Chemie (CO6) PubChem (44252896) PubChem (118286975) PubChem (124928939) PubChem (124928940) PubChem (124928942) PubChem (135070311) PubChem (170104447) PubChem (3036931) PubChem (808) PubChem (439277) PubChem (124928941) | |||
| 5 | SA, TA, UA, VA, WA... (A, B, C, D, E...) | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 162 - 421 (UniProt: P11181)
| PDB | External Database | Details |
|---|---|---|
| Gly 160 | - | cloning artifact |
| His 161 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 229812.6 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 8071.1 | |
| All* | Total formula weight | 237883.7 |
