2IH3
Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | FAB Heavy Chain | polymer | 219 | 23411.2 | 1 | Mus musculus (house mouse) | ||
2 | B | FAB Light Chain | polymer | 212 | 23435.7 | 1 | Mus musculus (house mouse) | ||
3 | C | Voltage-gated potassium channel | polymer | 122 | 13028.4 | 1 | UniProt (P0A334) Pfam (PF00520) Pfam (PF07885) In PDB | Streptomyces lividans | |
4 | C | POTASSIUM ION | non-polymer | 39.1 | 7 | Chemie (K) | |||
5 | C | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE | non-polymer | 442.7 | 1 | Chemie (1EM) | |||
6 | water | water | 18.0 | 266 | Chemie (HOH) |
Sequence modifications
C: 3 - 122 (UniProt: P0A334)
PDB | External Database | Details |
---|---|---|
Met 1 | - | cloning artifact |
Ala 2 | - | cloning artifact |
Ala 69 | Ser 69 | engineered mutation |
Cys 70 | Val 70 | engineered mutation |
Dal 77 | Gly 77 | modified residue |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 59875.4 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 716.4 | |
All* | Total formula weight | 60591.8 |