2IBI
Covalent Ubiquitin-USP2 Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Ubiquitin carboxyl-terminal hydrolase 2 | polymer | 374 | 42713.2 | 1 | UniProt (O75604) Pfam (PF00443) In PDB | Homo sapiens (human) | Ubiquitin thioesterase 2, Ubiquitin-specific-processing protease 2, Deubiquitinating enzyme 2, 41 kDa ubiquitin-specific protease |
| 2 | B | Ubiquitin | polymer | 75 | 8519.8 | 1 | UniProt (P62988) Pfam (PF00240) UniProt (by SIFTS) (P0CG48) In PDB | Homo sapiens (human) | |
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | B | ETHANAMINE | non-polymer | 45.1 | 1 | Chemie (NEH) | |||
| 5 | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A: 251 - 605 (UniProt: O75604)
| PDB | External Database | Details |
|---|---|---|
| Met 232 | - | initiating methionine |
| Gly 233 | - | cloning artifact |
| Ser 234 | - | cloning artifact |
| Ser 235 | - | cloning artifact |
| His 236 | - | expression tag |
| His 237 | - | expression tag |
| His 238 | - | expression tag |
| His 239 | - | expression tag |
| His 240 | - | expression tag |
| His 241 | - | expression tag |
| Ser 242 | - | cloning artifact |
| Ser 243 | - | cloning artifact |
| Gly 244 | - | cloning artifact |
| Leu 245 | - | cloning artifact |
| Val 246 | - | cloning artifact |
| Pro 247 | - | cloning artifact |
| Arg 248 | - | cloning artifact |
| Gly 249 | - | cloning artifact |
| Ser 250 | - | cloning artifact |
| Ala 472 | Glu 472 | engineered mutation |
| Ala 473 | Lys 473 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51233.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 110.5 | |
| All* | Total formula weight | 51343.5 |
