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2IAG

Crystal structure of human prostacyclin synthase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Prostacyclin synthasepolymer48255355.42UniProt (Q16647)
Pfam (PF00067)
Homo sapiens (human)Prostaglandin I2 synthase
2C, E
(A, B)
PROTOPORPHYRIN IX CONTAINING FEnon-polymer616.52Chemie (HEM)
3D
(B)
SODIUM IONnon-polymer23.01Chemie (NA)
4F, G
(A, B)
waterwater18.0435Chemie (HOH)
Sequence modifications
A, B: 23 - 500 (UniProt: Q16647)
PDBExternal DatabaseDetails
His 501-expression tag
His 502-expression tag
His 503-expression tag
His 504-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight110710.8
Non-Polymers*Number of molecules3
Total formula weight1256.0
All*Total formula weight111966.8
*Water molecules are not included.

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PDB entries from 2025-07-16

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