2I9P
Crystal structure of human hydroxyisobutyrate dehydrogenase complexed with NAD+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 3-hydroxyisobutyrate dehydrogenase | polymer | 319 | 33866.8 | 4 | UniProt (P31937) Pfam (PF03446) Pfam (PF14833) | Homo sapiens (human) | HIBADH |
| 2 | E, F, G, H (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) |
Sequence modifications
A, B, C, D: 41 - 336 (UniProt: P31937)
| PDB | External Database | Details |
|---|---|---|
| Met 18 | - | cloning artifact |
| His 19 | - | cloning artifact |
| His 20 | - | cloning artifact |
| His 21 | - | cloning artifact |
| His 22 | - | cloning artifact |
| His 23 | - | cloning artifact |
| His 24 | - | cloning artifact |
| Ser 25 | - | cloning artifact |
| Ser 26 | - | cloning artifact |
| Gly 27 | - | cloning artifact |
| Val 28 | - | cloning artifact |
| Asp 29 | - | cloning artifact |
| Leu 30 | - | cloning artifact |
| Gly 31 | - | cloning artifact |
| Thr 32 | - | cloning artifact |
| Glu 33 | - | cloning artifact |
| Asn 34 | - | cloning artifact |
| Leu 35 | - | cloning artifact |
| Tyr 36 | - | cloning artifact |
| Phe 37 | - | cloning artifact |
| Gln 38 | - | cloning artifact |
| Ser 39 | - | cloning artifact |
| Met 40 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 135467.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2653.7 | |
| All* | Total formula weight | 138121.1 |
