2I9B
Crystal structure of ATF-urokinase receptor complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Urokinase-type plasminogen activator | polymer | 145 | 16398.5 | 4 | UniProt (P00749) Pfam (PF00051) | Homo sapiens (human) | |
| 2 | E, F, G, H (E, F, G, H) | Urokinase plasminogen activator surface receptor | polymer | 279 | 31110.0 | 4 | UniProt (Q03405) Pfam (PF00021) | Homo sapiens (human) | uPAR, U- PAR, Monocyte activation antigen Mo3, CD87 antigen |
| 3 | I, J (I, J) | beta-D-mannopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G73474XW) | |||
| 4 | K, L (K, L) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | M, N (E, F) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | O, P, Q, R, S... (A, B, C, D, E...) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 143 (UniProt: P00749)
E, F, G, H: 1 - 277 (UniProt: Q03405)
| PDB | External Database | Details |
|---|---|---|
| Arg -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Arg -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
| Gln 162 | Asn 184 | engineered mutation |
| Gln 172 | Asn 194 | engineered mutation |
| Gln 200 | Asn 222 | engineered mutation |
| Gln 233 | Asn 255 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 190033.7 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2021.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 192247.7 |
