2I1Y
Crystal structure of the phosphatase domain of human PTP IA-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Receptor-type tyrosine-protein phosphatase | polymer | 301 | 34293.0 | 2 | UniProt (Q16849) Pfam (PF00102) | Homo sapiens (human) | R-PTP-N, PTP IA-2, Islet cell antigen 512, ICA 512, Islet cell autoantigen 3 |
| 2 | C, D (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 306 | Chemie (HOH) |
Sequence modifications
A, B: 681 - 979 (UniProt: Q16849)
| PDB | External Database | Details |
|---|---|---|
| Ser 679 | - | cloning artifact |
| Leu 680 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68586.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 68770.2 |
