2I0C
Crystal structure of the GluR6 ligand binding core dimer crosslinked by disulfide bonds between Y490C and L752C at 2.25 Angstroms Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Glutamate receptor, ionotropic kainate 2 | polymer | 259 | 29259.6 | 2 | UniProt (P42260) Pfam (PF10613) Pfam (PF00060) In PDB | Rattus norvegicus (Norway rat) | Glutamate receptor 6, GluR-6, GluR6 |
| 2 | A, B | GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GLU) | |||
| 3 | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 117 (UniProt: P42260)
A, B: 120 - 259 (UniProt: P42260)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Cys 94 | Tyr 521 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | linker |
| Thr 119 | - | linker |
| Cys 236 | Leu 783 | engineered mutation |
| Ser 259 | Glu 806 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58519.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 294.3 | |
| All* | Total formula weight | 58813.4 |
