2I0C

Crystal structure of the GluR6 ligand binding core dimer crosslinked by disulfide bonds between Y490C and L752C at 2.25 Angstroms Resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glutamate receptor, ionotropic kainate 2	polymer	259	29259.6	2	UniProt (P42260) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Norway rat)	Glutamate receptor 6, GluR-6, GluR6
2	C, D (A, B)	GLUTAMIC ACID	non-polymer		147.1	2	Chemie (GLU)
3	E, F (A, B)	water	water		18.0	204	Chemie (HOH)

Sequence modifications

A, B: 2 - 117 (UniProt: P42260)

PDB	External Database	Details
Gly 1	-	cloning artifact
Cys 94	Tyr 521	engineered mutation

A, B: 120 - 259 (UniProt: P42260)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker
Cys 236	Leu 783	engineered mutation
Ser 259	Glu 806	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58519.1
Non-Polymers*	Number of molecules	2
	Total formula weight	294.3
All*	Total formula weight	58813.4

*Water molecules are not included.