2HZY
Mouse fumarylacetoacetate hydrolase complexes with a transition-state mimic of the complete substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fumarylacetoacetase | polymer | 421 | 46296.7 | 2 | UniProt (P35505) Pfam (PF09298) Pfam (PF01557) | Mus musculus (house mouse) | Fumarylacetoacetate hydrolase, Beta-diketonase, FAA |
| 2 | C, L (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 3 | D, M (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 4 | E (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | F, G, H, I, J... (A, B) | NICKEL (II) ION | non-polymer | 58.7 | 10 | Chemie (NI) | |||
| 6 | K, S (A, B) | 4-(2-CARBOXYETHYL)(HYDROXY)PHOSPHORYL]-3-OXOBUTANOIC ACID | non-polymer | 238.1 | 2 | Chemie (DHJ) | |||
| 7 | T, U (A, B) | water | water | 18.0 | 996 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 419 (UniProt: P35505)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 92593.3 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1259.1 | |
| All* | Total formula weight | 93852.4 |
