2HZQ

Crystal structure of human apolipoprotein D (ApoD) in complex with progesterone

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Apolipoprotein D	polymer	174	19988.1	1	UniProt (P05090) Pfam (PF00061)	Homo sapiens (human)	Apo-D, ApoD
2	B (A)	PROGESTERONE	non-polymer		314.5	1	Chemie (STR)
3	C (A)	water	water		18.0	234	Chemie (HOH)

Sequence modifications

A: 3 - 169 (UniProt: P05090)

PDB	External Database	Details
Pro 23	Leu 43	engineered mutation
Mse 49	Met 69	modified residue
Mse 93	Met 113	modified residue
His 99	Trp 119	engineered mutation
Ser 116	Cys 136	engineered mutation
Ser 118	Ile 138	engineered mutation
Ser 120	Leu 140	engineered mutation
Val 133	Pro 153	engineered mutation
Ala 134	Asn 154	engineered mutation
Mse 157	Met 177	modified residue
Ala 170	-	expression tag
His 171	-	expression tag
His 172	-	expression tag
His 173	-	expression tag
His 174	-	expression tag
His 175	-	expression tag
His 176	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	19988.1
Non-Polymers*	Number of molecules	1
	Total formula weight	314.5
All*	Total formula weight	20302.6

*Water molecules are not included.