2HZQ

Crystal structure of human apolipoprotein D (ApoD) in complex with progesterone

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000302	biological_process	response to reactive oxygen species
A	0001525	biological_process	angiogenesis
A	0005319	molecular_function	lipid transporter activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0005783	cellular_component	endoplasmic reticulum
A	0006006	biological_process	glucose metabolic process
A	0006629	biological_process	lipid metabolic process
A	0006869	biological_process	lipid transport
A	0006950	biological_process	response to stress
A	0007420	biological_process	brain development
A	0008289	molecular_function	lipid binding
A	0010642	biological_process	negative regulation of platelet-derived growth factor receptor signaling pathway
A	0014012	biological_process	peripheral nervous system axon regeneration
A	0015485	molecular_function	cholesterol binding
A	0022626	cellular_component	cytosolic ribosome
A	0030425	cellular_component	dendrite
A	0042246	biological_process	tissue regeneration
A	0042308	biological_process	negative regulation of protein import into nucleus
A	0043025	cellular_component	neuronal cell body
A	0048471	cellular_component	perinuclear region of cytoplasm
A	0048662	biological_process	negative regulation of smooth muscle cell proliferation
A	0048678	biological_process	response to axon injury
A	0051895	biological_process	negative regulation of focal adhesion assembly
A	0060588	biological_process	negative regulation of lipoprotein lipid oxidation
A	0070062	cellular_component	extracellular exosome
A	0071638	biological_process	negative regulation of monocyte chemotactic protein-1 production
A	1900016	biological_process	negative regulation of cytokine production involved in inflammatory response
A	2000098	biological_process	negative regulation of smooth muscle cell-matrix adhesion
A	2000405	biological_process	negative regulation of T cell migration

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE STR A 300

Chain	Residue
A	THR34
A	ALA44
A	TYR46
A	ASN58
A	PHE89
A	TYR98
A	LEU129
A	HOH461

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:22171320, ECO:0000269|PubMed:7613477, ECO:0000269|PubMed:7918467

Chain	Residue	Details
A	ASN45

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19838169, ECO:0000269|PubMed:22171320, ECO:0000269|PubMed:7613477, ECO:0000269|PubMed:7918467

Chain	Residue	Details
A	ASN78

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