2HYY
Human Abl kinase domain in complex with imatinib (STI571, Glivec)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Proto-oncogene tyrosine-protein kinase ABL1 | polymer | 273 | 31678.3 | 4 | UniProt (P00519) Pfam (PF07714) In PDB | Homo sapiens (human) | p150, c-ABL, Abelson murine leukemia viral oncogene homolog 1 |
| 2 | A, B, C, D | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE | non-polymer | 493.6 | 4 | Chemie (STI) | |||
| 3 | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 126713.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1974.4 | |
| All* | Total formula weight | 128687.5 |
