2HU4
N1 neuraminidase in complex with oseltamivir 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Neuraminidase | polymer | 387 | 42429.2 | 8 | UniProt (Q6DPL2) Pfam (PF00064) | Influenza A virus | Neuraminidase NA |
| 2 | I, J, K, L, M... (A, B, C, D, E...) | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 8 | Chemie (G39) |
Sequence modifications
A, B, C, D, E, F, G, H: 83 - 470 (UniProt: Q6DPL2)
| PDB | External Database | Details |
|---|---|---|
| Tyr 252 | His 233 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 339433.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2274.8 | |
| All* | Total formula weight | 341708.2 |
