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2HTK

Structure of the Escherichia coli ClC chloride channel Y445A mutant and Fab complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
H(+)/Cl(-) exchange transporter clcApolymer47350298.32UniProt (P37019)
Pfam (PF00654)
Escherichia coli1ECCLC H+/CL- ANTIPORTER; CLC-EC1
2C, E
(C, E)
Fab fragment, Heavy chainpolymer22123693.92Pfam (PF07686)
Pfam (PF07654)
UniProt (by SIFTS) (Q4VBH1)
Mus musculus (house mouse)
3D, F
(D, F)
Fab fragment, Light chainpolymer21123088.42Mus musculus (house mouse)
4G, H
(A, B)
BROMIDE IONnon-polymer79.92Chemie (BR)
Sequence modifications
A, B: 1 - 473 (UniProt: P37019)
PDBExternal DatabaseDetails
Ala 445Tyr 445engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight194161.3
Non-Polymers*Number of molecules2
Total formula weight159.8
All*Total formula weight194321.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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