2HT4
Structure of the Escherichia coli ClC chloride channel Y445W mutant and Fab complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | H(+)/Cl(-) exchange transporter clcA | polymer | 473 | 50413.4 | 2 | UniProt (P37019) Pfam (PF00654) | Escherichia coli | 1ECCLC H+/CL- ANTIPORTER; CLC-EC1 |
| 2 | C, E (C, E) | Fab fragment, Heavy chain | polymer | 221 | 23693.9 | 2 | Pfam (PF07686) Pfam (PF07654) UniProt (by SIFTS) (Q4VBH1) | Mus musculus (house mouse) | |
| 3 | D, F (D, F) | Fab fragment, Light chain | polymer | 211 | 23088.4 | 2 | Mus musculus (house mouse) | ||
| 4 | G, H, I, J (A, B) | BROMIDE ION | non-polymer | 79.9 | 4 | Chemie (BR) |
Sequence modifications
A, B: 1 - 473 (UniProt: P37019)
| PDB | External Database | Details |
|---|---|---|
| Trp 445 | Tyr 445 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 194391.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 319.6 | |
| All* | Total formula weight | 194711.2 |
