2HQU
Human dUTPase in complex with alpha,beta-iminodUTP and magnesium ion
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Deoxyuridine 5'-triphosphate nucleotidohydrolase | polymer | 164 | 17771.1 | 3 | UniProt (P33316) Pfam (PF00692) | Homo sapiens (human) | dUTPase, dUTP pyrophosphatase |
| 2 | D, E, G, I (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | F, H, K (A, B, C) | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE | non-polymer | 467.2 | 3 | Chemie (DUP) | |||
| 4 | J (C) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | L, M, N (A, B, C) | water | water | 18.0 | 152 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 164 (UniProt: P33316)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | SEE REMARK 999 |
| Pro 2 | - | SEE REMARK 999 |
| Cys 3 | - | SEE REMARK 999 |
| Ser 4 | - | SEE REMARK 999 |
| Glu 5 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 53313.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1534.1 | |
| All* | Total formula weight | 54847.3 |
