2HMH
Crystal structure of SOCS3 in complex with gp130(pTyr757) phosphopeptide.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Suppressor of cytokine signaling 3 | polymer | 152 | 17043.0 | 1 | UniProt (O35718) Pfam (PF00017) In PDB | Mus musculus (house mouse) | SOCS-3, Cytokine-inducible SH2 protein 3, CIS-3, Protein EF-10 |
| 2 | B | Interleukin-6 receptor beta chain | polymer | 11 | 1289.3 | 1 | UniProt (Q00560) In PDB | IL-6R-beta, Interleukin 6 signal transducer, Membrane glycoprotein 130, gp130, CD130 antigen | |
| 3 | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence modifications
A: 15 - 130 (UniProt: O35718)
A: 131 - 162 (UniProt: O35718)
B: 753 - 763 (UniProt: Q00560)
| PDB | External Database | Details |
|---|---|---|
| Gly 11 | - | cloning artifact |
| Ser 12 | - | cloning artifact |
| Glu 13 | - | cloning artifact |
| Phe 14 | - | cloning artifact |
| Cas 97 | Cys 97 | modified residue |
| Cas 119 | Cys 119 | modified residue |
B: 753 - 763 (UniProt: Q00560)
| PDB | External Database | Details |
|---|---|---|
| Ptr 757 | Tyr 757 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 18332.3 | |
| All* | Total formula weight | 18332.3 |
