2HLZ

Crystal Structure of human ketohexokinase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Ketohexokinase	polymer	312	34306.4	4	UniProt (P50053) Pfam (PF00294)	Homo sapiens (human)	Hepatic fructokinase
2	AA, BA, CA, DA, E... (C, D, A, B)	UNKNOWN ATOM OR ION	non-polymer			32	Chemie (UNX)
3	KA, LA, MA, NA (A, B, C, D)	water	water		18.0	372	Chemie (HOH)

Sequence modifications

A, B, C, D: 5 - 298 (UniProt: P50053)

PDB	External Database	Details
Gly -13	-	cloning artifact
Ser -12	-	cloning artifact
Ser -11	-	cloning artifact
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
Ser -4	-	cloning artifact
Ser -3	-	cloning artifact
Gly -2	-	cloning artifact
Leu -1	-	cloning artifact
Val 0	-	cloning artifact
Pro 1	-	cloning artifact
Arg 2	-	cloning artifact
Gly 3	-	cloning artifact
Ser 4	-	cloning artifact
Ile 49	Val 49	conflict
Mse 60	Met 60	modified residue
Mse 63	Met 63	modified residue
Mse 149	Met 149	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	137225.6
Non-Polymers*	Number of molecules	32
	Total formula weight	0.0
All*	Total formula weight	137225.6

*Water molecules are not included.