2HKO
Crystal structure of LSD1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific histone demethylase 1 | polymer | 664 | 73887.5 | 1 | UniProt (O60341) Pfam (PF04433) Pfam (PF01593) | Homo sapiens (human) | Amine oxidase flavin-containing domain protein 2, BRAF35-HDAC complex protein BHC110 |
| 2 | B (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 3 | C (A) | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
A: 172 - 835 (UniProt: O60341)
| PDB | External Database | Details |
|---|---|---|
| Gln 594 | Arg 594 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 73887.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 785.5 | |
| All* | Total formula weight | 74673.0 |






