2HK5
Hck Kinase in Complex with Lck targetted Inhibitor PG-1009247
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tyrosine-protein kinase HCK | polymer | 270 | 30970.8 | 1 | UniProt (P08631) Pfam (PF07714) In PDB | Homo sapiens (human) | p59-HCK/p60-HCK, Hemopoietic cell kinase |
| 2 | A | 3-{[2-(1H-BENZIMIDAZOL-1-YL)-6-{[2-(DIETHYLAMINO)ETHYL]AMINO}PYRIMIDIN-4-YL]AMINO}-4-METHYLPHENOL | non-polymer | 431.5 | 1 | Chemie (1BM) | |||
| 3 | water | water | 18.0 | 231 | Chemie (HOH) |
Sequence modifications
A: 230 - 497 (UniProt: P08631)
| PDB | External Database | Details |
|---|---|---|
| Ala 229 | - | expression tag |
| Glu 498 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30970.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 431.5 | |
| All* | Total formula weight | 31402.4 |
