2HJH
Crystal Structure of the Sir2 deacetylase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | NAD-dependent histone deacetylase SIR2 | polymer | 354 | 40700.0 | 2 | UniProt (P06700) Pfam (PF04574) Pfam (PF02146) In PDB | Saccharomyces cerevisiae (baker's yeast) | Regulatory protein SIR2, Silent information regulator 2 |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | (2R,3R,4S,5R)-5-({[(R)-{[(R)-{[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL ACETATE | non-polymer | 601.4 | 2 | Chemie (XYQ) | |||
| 4 | A, B | NICOTINAMIDE | non-polymer | 122.1 | 2 | Chemie (NCA) | |||
| 5 | water | water | 18.0 | 517 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 81400.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1577.8 | |
| All* | Total formula weight | 82977.8 |
