2HEY
Crystal structure of murine OX40L bound to human OX40
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (F, G) | Tumor necrosis factor ligand superfamily member 4 | polymer | 152 | 17064.4 | 2 | UniProt (P43488) | Mus musculus (house mouse) | OX40 ligand, OX40L, CD252 antigen |
| 2 | C, D (R, T) | Tumor necrosis factor receptor superfamily member 4 | polymer | 146 | 15808.8 | 2 | UniProt (P43489) Pfam (PF00020) | Homo sapiens (human) | OX40L receptor, ACT35 antigen, TAX transcriptionally-activated glycoprotein 1 receptor, CD134 antigen |
| 3 | E (R) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F, G, H, I (F, G, R, T) | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence modifications
F, G: 51 - 198 (UniProt: P43488)
R, T: 29 - 170 (UniProt: P43489)
| PDB | External Database | Details |
|---|---|---|
| Gly 47 | - | cloning artifact |
| Ser 48 | - | cloning artifact |
| His 49 | - | cloning artifact |
| Met 50 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | cloning artifact |
| Ser 26 | - | cloning artifact |
| His 27 | - | cloning artifact |
| Met 28 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 65746.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 65842.4 |
