Functional Information from GO Data
| Chain | GOid | namespace | contents |
| F | 0005125 | molecular_function | cytokine activity |
| F | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| F | 0006955 | biological_process | immune response |
| F | 0016020 | cellular_component | membrane |
| G | 0005125 | molecular_function | cytokine activity |
| G | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| G | 0006955 | biological_process | immune response |
| G | 0016020 | cellular_component | membrane |
| R | 0005031 | molecular_function | tumor necrosis factor receptor activity |
| R | 0006954 | biological_process | inflammatory response |
| T | 0005031 | molecular_function | tumor necrosis factor receptor activity |
| T | 0006954 | biological_process | inflammatory response |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 R 171 |
| Chain | Residue |
| R | ARG41 |
| R | CYS43 |
| R | HIS44 |
| R | ARG47 |
| R | ASN61 |
| R | THR62 |
| R | HOH178 |
Functional Information from PROSITE/UniProt
| site_id | PS00251 |
| Number of Residues | 17 |
| Details | THD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. VvIKcDGLYIIylKGsF |
| Chain | Residue | Details |
| F | VAL94-PHE110 | |
| site_id | PS00652 |
| Number of Residues | 34 |
| Details | TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Cvgdt..Ypsndr.....C..Che.Crpgngmvsr..Csrsq..NTVC |
| Chain | Residue | Details |
| R | CYS31-CYS64 | |
| R | CYS64-CYS107 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 234 |
| Details | Domain: {"description":"THD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01387","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16905106","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 70 |
| Details | Repeat: {"description":"TNFR-Cys 1"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 82 |
| Details | Repeat: {"description":"TNFR-Cys 2"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 36 |
| Details | Repeat: {"description":"TNFR-Cys 3; truncated"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
