2HEN
Crystal Structure of the EphB2 Receptor Kinase domain in complex with ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ephrin type-B receptor 2 | polymer | 286 | 32285.1 | 4 | UniProt (P54763) Pfam (PF07714) | Mus musculus (house mouse) | Tyrosine-protein kinase receptor EPH-3, Neural kinase, Nuk receptor tyrosine kinase, SEK-3 |
| 2 | E, G, I, K (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | F, H, J, L (A, B, C, D) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 301 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 622 - 906 (UniProt: P54763)
| PDB | External Database | Details |
|---|---|---|
| Ser 621 | - | cloning artifact |
| Ala 754 | Asp 754 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 129140.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1806.0 | |
| All* | Total formula weight | 130946.3 |
