2HE3
Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutathione peroxidase 2 | polymer | 208 | 24115.4 | 1 | UniProt (P18283) Pfam (PF00255) | Homo sapiens (human) | GSHPx-2, GPx-2, Glutathione peroxidase-gastrointestinal, GSHPx-GI, Glutathione peroxidase- related protein 2, Gastrointestinal glutathione peroxidase, GPRP |
| 2 | B, C (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | D (A) | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
A: 4 - 188 (UniProt: P18283)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | cloning artifact |
| His -18 | - | cloning artifact |
| His -17 | - | cloning artifact |
| His -16 | - | cloning artifact |
| His -15 | - | cloning artifact |
| His -14 | - | cloning artifact |
| His -13 | - | cloning artifact |
| Ser -12 | - | cloning artifact |
| Ser -11 | - | cloning artifact |
| Gly -10 | - | cloning artifact |
| Val -9 | - | cloning artifact |
| Asp -8 | - | cloning artifact |
| Leu -7 | - | cloning artifact |
| Gly -6 | - | cloning artifact |
| Thr -5 | - | cloning artifact |
| Glu -4 | - | cloning artifact |
| Asn -3 | - | cloning artifact |
| Leu -2 | - | cloning artifact |
| Tyr -1 | - | cloning artifact |
| Phe 0 | - | cloning artifact |
| Gln 1 | - | cloning artifact |
| Ser 2 | - | cloning artifact |
| Met 3 | - | cloning artifact |
| Asn 15 | Ser 15 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24115.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 24186.3 |
