2HD0
Structure of the catalytic domain of hepatitis C virus NS2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Protease NS2-3 (p23) | polymer | 128 | 13926.4 | 12 | UniProt (P27958) Pfam (PF01538) | Hepatitis C virus | |
| 2 | M, N, O, P, Q... (A, B, C, F, H...) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 11 | Chemie (BOG) | |||
| 3 | U (I) | DECYL-BETA-D-MALTOPYRANOSIDE | non-polymer | 482.6 | 1 | Chemie (DMU) PubChem (24776995) PubChem (16396531) PubChem (45253991) PubChem (45254001) PubChem (24802064) PubChem (56845266) PubChem (58112552) PubChem (45253971) PubChem (59518661) PubChem (49866911) PubChem (70796430) PubChem (70839938) PubChem (71307274) PubChem (3637526) PubChem (5288091) PubChem (95370473) PubChem (98046563) PubChem (5288728) PubChem (101207920) PubChem (126735852) PubChem (95370474) PubChem (95370475) PubChem (95370476) PubChem (98046559) PubChem (98046561) PubChem (100941450) PubChem (100950626) PubChem (102219024) PubChem (118704896) PubChem (123134571) PubChem (124867949) PubChem (124867950) PubChem (124867951) PubChem (124867952) PubChem (126731012) PubChem (126731036) PubChem (126735974) PubChem (168490163) | |||
| 4 | AA, BA, CA, DA, EA... (C, D, E, F, G...) | water | water | 18.0 | 176 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 2 - 217 (UniProt: P27958)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Ser 2 | - | cloning artifact |
| His 3 | - | cloning artifact |
| Met 4 | - | cloning artifact |
| Tyr 139 | Cys 947 | variant |
| Thr 145 | Ala 953 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 167116.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3698.6 | |
| All* | Total formula weight | 170815.1 |
