2HD0
Structure of the catalytic domain of hepatitis C virus NS2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| C | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| D | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| E | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| F | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| G | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| H | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| I | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| J | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| K | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| L | 0004197 | molecular_function | cysteine-type endopeptidase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 240 |
| Details | Region: {"description":"Interaction with host SCPS1","evidences":[{"source":"UniProtKB","id":"Q99IB8","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Active site: {"description":"For protease NS2 activity; shared with dimeric partner","evidences":[{"source":"PROSITE-ProRule","id":"PRU01030","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16862121","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8248148","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Active site: {"description":"For protease NS2 activity; shared with dimeric partner","evidences":[{"source":"PROSITE-ProRule","id":"PRU01030","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Lipidation: {"description":"S-palmitoyl cysteine; by host","evidences":[{"source":"PubMed","id":"31597774","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | |
| Details | M-CSA 776 |
| Chain | Residue | Details |
| site_id | MCSA10 |
| Number of Residues | |
| Details | M-CSA 776 |
| Chain | Residue | Details |
| site_id | MCSA11 |
| Number of Residues | |
| Details | M-CSA 776 |
| Chain | Residue | Details |
| site_id | MCSA12 |
| Number of Residues | |
| Details | M-CSA 776 |
| Chain | Residue | Details |
| site_id | MCSA2 |
| Number of Residues | |
| Details | M-CSA 776 |
| Chain | Residue | Details |
| site_id | MCSA3 |
| Number of Residues | |
| Details | M-CSA 776 |
| Chain | Residue | Details |
| site_id | MCSA4 |
| Number of Residues | |
| Details | M-CSA 776 |
| Chain | Residue | Details |
| site_id | MCSA5 |
| Number of Residues | |
| Details | M-CSA 776 |
| Chain | Residue | Details |
| site_id | MCSA6 |
| Number of Residues | |
| Details | M-CSA 776 |
| Chain | Residue | Details |
| site_id | MCSA7 |
| Number of Residues | |
| Details | M-CSA 776 |
| Chain | Residue | Details |
| site_id | MCSA8 |
| Number of Residues | |
| Details | M-CSA 776 |
| Chain | Residue | Details |
| site_id | MCSA9 |
| Number of Residues | |
| Details | M-CSA 776 |
| Chain | Residue | Details |
