2HAN
Structural basis of heterodimeric ecdysteroid receptor interaction with natural response element hsp27 gene promoter
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | 5'-D(*CP*AP*AP*GP*GP*GP*TP*TP*CP*AP*AP*TP*GP*CP*AP*CP*TP*TP*GP*T)-3' | polymer | 20 | 6149.0 | 1 | |||
| 2 | B (D) | 5'-D(*GP*AP*CP*AP*AP*GP*TP*GP*CP*AP*TP*TP*GP*AP*AP*CP*CP*CP*TP*T)-3' | polymer | 20 | 6118.0 | 1 | |||
| 3 | C (A) | Protein ultraspiracle | polymer | 93 | 10818.4 | 1 | UniProt (P20153) Pfam (PF00105) | Drosophila melanogaster (fruit fly) | XR2C, Chorion factor 1 |
| 4 | D (B) | Ecdysone receptor | polymer | 119 | 13520.8 | 1 | UniProt (P34021) Pfam (PF00105) | Drosophila melanogaster (fruit fly) | Ecdysteroid receptor, 20-hydroxy-ecdysone receptor, 20E receptor, EcRH |
| 5 | E, F, G, H (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 6 | I, J, K, L (C, D, A, B) | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A: -3 - 82 (UniProt: P20153)
B: -1 - 108 (UniProt: P34021)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | cloning artifact |
| Ser -4 | - | cloning artifact |
| Gly 83 | - | cloning artifact |
| Ile 84 | - | cloning artifact |
| His 85 | - | cloning artifact |
| Arg 86 | - | cloning artifact |
| Asp 87 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | cloning artifact |
| Ser -2 | - | cloning artifact |
| Ser 109 | - | cloning artifact |
| Pro 110 | - | cloning artifact |
| Gly 111 | - | cloning artifact |
| Ile 112 | - | cloning artifact |
| His 113 | - | cloning artifact |
| Arg 114 | - | cloning artifact |
| Asp 115 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 36606.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 36867.9 |
