2HA6
Crystal structure of mutant S203A of mouse acetylcholinesterase complexed with succinylcholine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Acetylcholinesterase | polymer | 543 | 59748.5 | 2 | UniProt (P21836) Pfam (PF00135) In PDB | Mus musculus (house mouse) | AChE |
| 2 | A, B | 2,2'-[(1,4-DIOXOBUTANE-1,4-DIYL)BIS(OXY)]BIS(N,N,N-TRIMETHYLETHANAMINIUM) | non-polymer | 290.4 | 4 | Chemie (SCK) | |||
| 3 | A | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
| 4 | A | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
| 5 | water | water | 18.0 | 624 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 543 (UniProt: P21836)
| PDB | External Database | Details |
|---|---|---|
| Ala 203 | Ser 234 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 119497.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1504.0 | |
| All* | Total formula weight | 121001.0 |
