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2H8H

Src kinase in complex with a quinazoline inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AProto-oncogene tyrosine-protein kinase Srcpolymer53559855.41UniProt (P12931)
Pfam (PF00018)
Pfam (PF00017)
Pfam (PF07714)
In PDB
Homo sapiens (human)p60-Src, c- Src, pp60c-src
2AN-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINEnon-polymer542.01Chemie (H8H)
3waterwater18.0221Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight59855.4
Non-Polymers*Number of molecules1
Total formula weight542.0
All*Total formula weight60397.4
*Water molecules are not included.

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PDB entries from 2024-03-27

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