2H7D
Solution structure of the talin F3 domain in complex with a chimeric beta3 integrin-PIP kinase peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Talin-1 | polymer | 101 | 11475.3 | 1 | UniProt (P54939) Pfam (PF02174) | Gallus gallus (chicken) | |
| 2 | B (B) | Chimera of 24-mer peptide from Integrin beta-3 and 10-mer peptide from Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma | polymer | 34 | 4279.8 | 1 | UniProt (P05106) UniProt (O70161) | Chimera of beta3-integrin and PIP-kinase |
Sequence modifications
A: 309 - 405 (UniProt: P54939)
B: 716 - 739 (UniProt: P05106)
B: 740 - 749 (UniProt: O70161)
| PDB | External Database | Details |
|---|---|---|
| Pro 305 | - | cloning artifact |
| Leu 306 | - | cloning artifact |
| Gly 307 | - | cloning artifact |
| Ser 308 | - | cloning artifact |
| Ser 336 | Cys 336 | engineered mutation |
B: 740 - 749 (UniProt: O70161)
| PDB | External Database | Details |
|---|---|---|
| Ptr 741 | Tyr 644 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 15755.1 | |
| All* | Total formula weight | 15755.1 |
