2H5I
Crystal structure of caspase-3 with inhibitor Ac-DEVD-Cho
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | caspase-3, p17 subunit | polymer | 146 | 16524.8 | 1 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (human) | CASP-3, Apopain, Cysteine protease CPP32, Yama protein, CPP-32, SREBP cleavage activity 1, SCA-1 |
| 2 | B (B) | caspase-3, p12 subunit | polymer | 95 | 11258.0 | 1 | UniProt (P42574) Pfam (PF00656) | Homo sapiens (human) | |
| 3 | C (C) | Ac-DEV(ASJ) | polymer | 5 | 488.5 | 1 | BIRD (PRD_000422) | ||
| 4 | D, E, F (A, B, C) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence modifications
B: 184 - 277 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| His 278 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 28271.3 | |
| All* | Total formula weight | 28271.3 |
