2H44
Crystal structure of PDE5A1 in complex with icarisid II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cGMP-specific 3',5'-cyclic phosphodiesterase | polymer | 326 | 37788.5 | 1 | UniProt (O76074) Pfam (PF00233) | Homo sapiens (human) | CGB-PDE, cGMP-binding cGMP-specific phosphodiesterase |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | 5,7-DIHYDROXY-2-(4-METHOXYPHENYL)-8-(3-METHYLBUTYL)-4-OXO-4H-CHROMEN-3-YL 6-DEOXY-ALPHA-L-MANNOPYRANOSIDE | non-polymer | 516.5 | 1 | Chemie (7CA) | |||
| 5 | E (A) | water | water | 18.0 | 231 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37788.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 606.3 | |
| All* | Total formula weight | 38394.8 |
