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2H40

Crystal structure of the catalytic domain of unliganded PDE5

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
cGMP-specific 3',5'-cyclic phosphodiesterasepolymer32637788.51UniProt (O76074)
Pfam (PF00233)
Homo sapiens (human)CGB-PDE, cGMP-binding cGMP-specific phosphodiesterase
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D
(A)
waterwater18.0148Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37788.5
Non-Polymers*Number of molecules2
Total formula weight89.7
All*Total formula weight37878.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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