2H1L
The Structure of the Oncoprotein SV40 Large T Antigen and p53 Tumor Suppressor Complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Large T antigen | polymer | 370 | 42645.4 | 12 | UniProt (Q9DH70) Pfam (PF06431) UniProt (by SIFTS) (P03070) In PDB | Simian virus 40 | |
2 | M, N, O, P, Q... | Cellular tumor antigen p53 | polymer | 203 | 22802.9 | 12 | UniProt (Q9NP68) Pfam (PF00870) UniProt (by SIFTS) (P04637) In PDB | Homo sapiens (human) | Tumor suppressor p53, Phosphoprotein p53, Antigen NY-CO-13 |
3 | C, D, E, F, G... | ZINC ION | non-polymer | 65.4 | 24 | Chemie (ZN) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 260 - 627 (UniProt: Q9DH70)
M, N, O, P, Q, R, S, T, U, V, W, X: 92 - 292 (UniProt: Q9NP68)
PDB | External Database | Details |
---|---|---|
Gly 258 | - | cloning artifact |
Ser 259 | - | cloning artifact |
PDB | External Database | Details |
---|---|---|
Gly 90 | - | cloning artifact |
Ser 91 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 24 |
Total formula weight | 785380.3 | |
Non-Polymers* | Number of molecules | 24 |
Total formula weight | 1569.8 | |
All* | Total formula weight | 786950.2 |