2H1L

The Structure of the Oncoprotein SV40 Large T Antigen and p53 Tumor Suppressor Complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Large T antigen	polymer	370	42645.4	12	UniProt (Q9DH70) Pfam (PF06431) UniProt (by SIFTS) (P03070)	Simian virus 40
2	M, N, O, P, Q... (M, N, O, P, Q...)	Cellular tumor antigen p53	polymer	203	22802.9	12	UniProt (Q9NP68) Pfam (PF00870) UniProt (by SIFTS) (P04637)	Homo sapiens (human)	Tumor suppressor p53, Phosphoprotein p53, Antigen NY-CO-13
3	AA, BA, CA, DA, EA... (C, D, E, F, G...)	ZINC ION	non-polymer		65.4	24	Chemie (ZN)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 260 - 627 (UniProt: Q9DH70)

PDB	External Database	Details
Gly 258	-	cloning artifact
Ser 259	-	cloning artifact

M, N, O, P, Q, R, S, T, U, V, W, X: 92 - 292 (UniProt: Q9NP68)

PDB	External Database	Details
Gly 90	-	cloning artifact
Ser 91	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	785380.3
Non-Polymers*	Number of molecules	24
	Total formula weight	1569.8
All*	Total formula weight	786950.2

*Water molecules are not included.