2GUO
Human Class I MHC HLA-A2 in complex with the native nonameric Melan-A/MART-1(27-35) peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | HLA class I histocompatibility antigen, A-2 alpha chain | polymer | 275 | 31854.2 | 2 | UniProt (Q9TQH5) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) | Homo sapiens (human) | MHC class I antigen A*2 |
| 2 | B, E (B, E) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C, F (C, F) | Peptide | polymer | 9 | 814.0 | 2 | UniProt (Q16655) | MART-1, Melan-A protein, Antigen SK29-AA, Antigen LB39-AA | |
| 4 | G, H, I, K (A, D, E) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | J (E) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | L, M, N, O, P... (A, B, C, D, E...) | water | water | 18.0 | 555 | Chemie (HOH) |
Sequence modifications
B, E: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 89095.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 391.4 | |
| All* | Total formula weight | 89486.4 |
