2GS3
Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 4(GPX4)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phospholipid hydroperoxide glutathione peroxidase | polymer | 185 | 21184.3 | 1 | UniProt (P36969) Pfam (PF00255) | Homo sapiens (human) | PHGPx, GPX-4 |
| 2 | B (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | C (A) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A: 36 - 197 (UniProt: P36969)
| PDB | External Database | Details |
|---|---|---|
| Met 13 | - | cloning artifact |
| His 14 | - | expression tag |
| His 15 | - | expression tag |
| His 16 | - | expression tag |
| His 17 | - | expression tag |
| His 18 | - | expression tag |
| His 19 | - | expression tag |
| Ser 20 | - | cloning artifact |
| Ser 21 | - | cloning artifact |
| Gly 22 | - | cloning artifact |
| Val 23 | - | cloning artifact |
| Asp 24 | - | cloning artifact |
| Leu 25 | - | cloning artifact |
| Gly 26 | - | cloning artifact |
| Thr 27 | - | cloning artifact |
| Glu 28 | - | cloning artifact |
| Asn 29 | - | cloning artifact |
| Leu 30 | - | cloning artifact |
| Tyr 31 | - | cloning artifact |
| Phe 32 | - | cloning artifact |
| Gln 33 | - | cloning artifact |
| Ser 34 | - | cloning artifact |
| Met 35 | - | cloning artifact |
| Gly 73 | Cys 73 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21184.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 21219.8 |
