2GS3

Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 4(GPX4)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004601	molecular_function	peroxidase activity
A	0006979	biological_process	response to oxidative stress

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 201

Chain	Residue
A	GLY73
A	GLY74
A	LYS75
A	ASN164

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Functional Information from PROSITE/UniProt

site_id	PS00763
Number of Residues	8
Details	GLUTATHIONE_PEROXID_2 Glutathione peroxidases signature 2. LAFPCNQF

Chain	Residue	Details
A	LEU98-PHE105

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:O70325

Chain	Residue	Details
A	GLY73

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P36970

Chain	Residue	Details
A	SER40

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1gp1

Chain	Residue	Details
A	GLN108
A	TRP163

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