2GOO
Ternary Complex of BMP-2 bound to BMPR-Ia-ECD and ActRII-ECD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Bone morphogenetic protein 2 | polymer | 114 | 12923.9 | 2 | UniProt (P12643) Pfam (PF00019) | Homo sapiens (human) | BMP-2, BMP-2A |
| 2 | B, E (B, E) | Bone morphogenetic protein receptor type IA | polymer | 131 | 14344.0 | 2 | UniProt (P36894) Pfam (PF01064) | Homo sapiens (human) | Serine/threonine-protein kinase receptor R5, SKR5, Activin receptor-like kinase 3, ALK-3, CD292 antigen |
| 3 | C, F (C, F) | Activin receptor type 2A | polymer | 102 | 12019.4 | 2 | UniProt (P27038) Pfam (PF01064) | Mus musculus (house mouse) | Activin receptor type IIA, ACTR-IIA |
| 4 | G, H, I, J (C, F) | 2-acetamido-2-deoxy-alpha-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NDG) | |||
| 5 | K, L, M, N, O... (A, B, C, D, E...) | water | water | 18.0 | 327 | Chemie (HOH) |
Sequence modifications
B, E: 1 - 129 (UniProt: P36894)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 78574.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 79459.5 |
