2GOO

Ternary Complex of BMP-2 bound to BMPR-Ia-ECD and ActRII-ECD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0008083	molecular_function	growth factor activity
B	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
B	0016020	cellular_component	membrane
C	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
C	0005524	molecular_function	ATP binding
C	0007178	biological_process	cell surface receptor protein serine/threonine kinase signaling pathway
C	0016020	cellular_component	membrane
D	0005576	cellular_component	extracellular region
D	0008083	molecular_function	growth factor activity
E	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
E	0016020	cellular_component	membrane
F	0004675	molecular_function	transmembrane receptor protein serine/threonine kinase activity
F	0005524	molecular_function	ATP binding
F	0007178	biological_process	cell surface receptor protein serine/threonine kinase signaling pathway
F	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00250
Number of Residues	16
Details	TGF_BETA_1 TGF-beta family signature. IvaPpgYhafyChGeC

Chain	Residue	Details
A	ILE32-CYS47

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) (high mannose) asparagine","evidences":[{"source":"PubMed","id":"9265423","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Region: {"description":"Mediates specificity for BMP ligand","evidences":[{"source":"PubMed","id":"22799562","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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